David Adams Selected Research

Polyneuropathies (Polyneuropathy)

1/2022	Patisiran treatment in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy after liver transplantation.
6/2021	Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy.
4/2021	Hematopoietic stem cell transplantation in chronic inflammatory demyelinating polyneuropathy: French experience about four patients, under the behalf of French society for bone marrow transplantation.
1/2021	Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study.
1/2021	Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis.
1/2021	Inflammatory demyelinating polyneuropathies and lymphoma: clues to diagnosis and therapy.
10/2020	Conjunctival lymphangiectasia as a biomarker of severe systemic disease in Ser77Tyr hereditary transthyretin amyloidosis.
10/2020	Hereditary transthyretin amyloidosis: current treatment.
9/2020	Quality of life outcomes in APOLLO, the phase 3 trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis.
3/2020	Analysis of autonomic outcomes in APOLLO, a phase III trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis.

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David Adams Research Topics

Disease

29	Polyneuropathies (Polyneuropathy) 01/2022 - 11/2007
26	Amyloidosis 09/2022 - 07/2006
18	Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy) 01/2019 - 07/2004
12	Transthyretin-Related Hereditary Amyloidosis 01/2022 - 08/2013
10	Disease Progression 09/2022 - 07/2004
7	Amyloid Plaque 01/2018 - 07/2004
6	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/2021 - 05/2016
5	Neoplasms (Cancer) 10/2021 - 08/2005
5	Chronic Pancreatitis 01/2021 - 07/2013
5	Undiagnosed Diseases 01/2019 - 04/2012
5	Amyloid Neuropathies (Amyloid Neuropathy) 10/2018 - 10/2012
4	Cardiomyopathies (Cardiomyopathy) 10/2020 - 10/2012
4	Infections 01/2020 - 06/2009
3	Diabetic Neuropathies (Diabetic Neuropathy) 01/2022 - 09/2017
3	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2021 - 10/2016
3	Pain (Aches) 01/2019 - 08/2014
3	Stroke (Strokes) 12/2018 - 05/2011
3	Hemorrhage 01/2018 - 02/2003
3	Familial Amyloidosis (Hereditary Amyloidosis) 04/2014 - 06/2012
3	Peripheral Nervous System Diseases (PNS Diseases) 03/2013 - 09/2012
3	Restrictive Cardiomyopathy 10/2012 - 07/2006
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 09/2013
2	Nervous System Diseases (Neurological Disorders) 01/2022 - 05/2016
2	Gastroparesis 01/2021 - 01/2021
2	Pancreatitis 01/2021 - 07/2013
2	Axial Spondyloarthritis 01/2021 - 01/2020
2	Lymphoma (Lymphomas) 01/2021 - 05/2011
2	Weight Gain 01/2021 - 05/2016
2	Polyradiculoneuropathy (Polyradiculoneuritis) 01/2020 - 01/2020
2	Inflammation (Inflammations) 01/2020 - 10/2013
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 12/2019 - 02/2005
2	Fibrosis (Cirrhosis) 12/2019 - 01/2017
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 01/2018
2	Rare Diseases (Rare Disease) 01/2019 - 01/2016
2	Brain Diseases (Brain Disorder) 01/2019 - 06/2016
2	Body Weight (Weight, Body) 01/2018 - 08/2013
2	Progressive Multifocal Leukoencephalopathy 01/2017 - 05/2013
2	Demyelinating Diseases (Demyelinating Disease) 09/2016 - 12/2012
2	Necrosis 02/2015 - 10/2013
2	Motor Neuron Disease (Primary Lateral Sclerosis) 09/2013 - 01/2013
2	Heart Failure 10/2012 - 08/2012
1	Malocclusion (Crossbite) 10/2022
1	Cardiogenic Shock 07/2022
1	Obstructive Sleep Apnea 01/2022
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022
1	Porphyrias (Porphyria) 01/2022
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2022
1	Huntington Disease (Huntington's Disease) 01/2022
1	Synucleinopathies 01/2022
1	Tauopathies 01/2022
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2022
1	COVID-19 10/2021
1	Meretoja syndrome 10/2021

Drug/Important Bio-Agent (IBA)

42	Prealbumin (Transthyretin)IBA 09/2022 - 07/2004
13	patisiranIBA 01/2022 - 08/2013
11	Amyloid (Amyloid Fibrils)IBA 09/2022 - 07/2006
10	Proteins (Proteins, Gene)FDA Link 06/2021 - 08/2005
10	Biomarkers (Surrogate Marker)IBA 01/2021 - 08/2005
6	Pharmaceutical PreparationsIBA 09/2022 - 12/2008
4	Monoclonal AntibodiesIBA 01/2020 - 09/2012
4	Intravenous Immunoglobulins (IVIG)FDA Link 06/2019 - 10/2007
4	tafamidisIBA 01/2015 - 09/2012
3	Antisense OligonucleotidesIBA 01/2022 - 10/2012
3	Uridine Diphosphate (UDP)IBA 01/2019 - 04/2012
2	VaccinesIBA 10/2021 - 10/2020
2	Small Interfering RNA (siRNA)IBA 01/2021 - 09/2015
2	ProteomeIBA 01/2021 - 02/2015
2	ixekizumabIBA 01/2021 - 01/2020
2	Sucrose (Saccharose)IBA 06/2019 - 05/2016
2	OligosaccharidesIBA 01/2019 - 04/2014
2	Insulin (Novolin)FDA Link 04/2018 - 07/2013
2	Opioid Analgesics (Opioids)IBA 04/2018 - 08/2014
2	3-Iodobenzylguanidine (Iobenguane)IBA 01/2018 - 12/2016
2	Doxycycline (Periostat)FDA LinkGeneric 01/2015 - 09/2012
2	ursodoxicoltaurineIBA 01/2015 - 09/2012
2	Immunoglobulins (Immunoglobulin)IBA 04/2014 - 05/2011
2	EnzymesIBA 04/2014 - 04/2013
2	SteroidsIBA 10/2013 - 05/2011
2	Natalizumab (Tysabri)FDA Link 05/2013 - 05/2013
2	Biological ProductsIBA 03/2013 - 09/2012
2	LigandsIBA 12/2010 - 11/2007
1	AmyloseIBA 09/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 10/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021
1	Immune Checkpoint InhibitorsIBA 10/2021

Therapy/Procedure

23	Therapeutics 09/2022 - 08/2006
16	Liver Transplantation 09/2022 - 07/2004
6	RNAi Therapeutics 09/2020 - 08/2013
3	Pancreatectomy 01/2021 - 07/2013
3	Autologous Transplantation 04/2018 - 03/2003
3	Denervation 01/2018 - 07/2006
2	Biological Therapy 01/2021 - 01/2017
2	Immunotherapy 10/2020 - 10/2016
2	Blood Transfusion (Blood Transfusions) 08/2012 - 06/2009
1	Fixed Orthodontic Appliances 10/2022
1	Extracorporeal Membrane Oxygenation 07/2022
1	Continuous Positive Airway Pressure 01/2022
1	Hematopoietic Stem Cell Transplantation 04/2021
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 04/2021